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Uses

INDICATIONS

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Micronase (Glyburide) can be an oral diabetes medicine that helps control blood sugar.

Glyburide is utilized to treat diabetes type 2 symptoms.

This medicine is not for treating type 1 diabetes.

Glyburide could also be used for other purposes unlisted within this medication guide.

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INSTRUCTIONS

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Take the same manner prescribed from your doctor. Do not take in larger or smaller amounts or longer than recommended. Follow the directions on the prescription label. Your doctor may occasionally improve your dose to ensure that you acquire the best results.

Take glyburide along with your first meal through the day, unless your physician tells you otherwise.

Your blood glucose levels must be checked often, and you might need other blood tests at your doctor's office. Visit a medical expert regularly.
Know the warning signs of low blood sugar levels (hypoglycemia) and the way to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a source of sugar obtainable in case you might have signs and symptoms of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you've severe hypoglycemia and should not eat or drink, make use of an injection of glucagon. Your doctor can provide you with a prescription for any glucagon emergency injection kit and show you how you can supply the injection.

Also watch for warning signs of blood sugar levels which is excessive (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and fat loss.

Check your blood glucose carefully during a period of stress or illness, should you travel, exercise more than usual, are drinking alcoholic beverages, or skip meals. These things may affect your blood sugar levels as well as your dose needs may also change.

Your doctor may wish one to stop taking glyburide to get a short time should you get ill, possess a fever or infection, or if you might have surgical procedures or a medical emergency.
Ask your physician the way to adjust your glyburide dose as needed. Do not improve your medication dose or schedule without your physician's advice.

If you will find any adjustments to the brand, strength, or kind of glyburide you employ, your dosage needs may change. Always check your refills to successfully have received the right logo and kind of medicine prescribed from your doctor.

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DOSAGE

Take as prescribed from your doctor.

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STORAGE

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Store at room temperature, shielded from moisture, heat, and light-weight.

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Active ingredient: Glyburide

Side Effects

Stop using glyburide and acquire emergency medical help if you've got these warning signs of a hypersensitivity: hives; breathlessness; swelling of the face, lips, tongue, or throat. Stop taking medicines and call your medical professional at the same time if you have these serious unwanted side effects:

nausea, stomach pain, low fever, loss in appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots under your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious unwanted side effects might include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete listing of side effects among others may occur. Call your physician for medical health advice about negative effects.

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Precautions

You should avoid using prescription drugs in the event you are allergic to glyburide, or:

in case you are receiving treatment with bosentan (Tracleer);

if you've type 1 diabetes; or

if you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

To be sure you can safely take glyburide, tell your physician if you might have these other conditions:

hemolytic anemia (too little red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

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liver or kidney disease;

in the event you are allergic to sulfa drugs; or

if you might have been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may increase your risk of serious cardiovascular disease. However, not taking care of your diabetes can damage your heart and other organs. Talk to a medical expert regarding the risks and important things about taking care of your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an baby. Similar diabetes medications have caused severe hypoglycemia in infants whose mothers had used the medication near the period of delivery. Tell your physician if you are pregnant or plan to get pregnant while using the this medication. It is not known whether glyburide passes into breast milk or if it could possibly harm a nursing baby.

Do not use medicines without telling your doctor should you are breast-feeding an infant. Older adults might be very likely to have low blood sugar levels while taking glyburide.

 

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Important safety information:

You must avoid using this medication if you are allergic to glyburide, should you are being treated with bosentan (Tracleer), if you've got type 1 diabetes, or in case you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

Before taking glyburide, tell your medical professional in case you are allergic to sulfa drugs, if you've been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (an absence of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to never let your blood glucose levels get too low. Low blood glucose levels (hypoglycemia) can take place should you skip dinner, exercise a long time, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and good friends know the best way to assist you in an emergency.

Drug interactions

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Tell your medical professional about all other medications you have, especially:

a blood thinner for example warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor including enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others; or

an antibiotic like ciprofloxacin (Cipro), levofloxacin (Levaquin), yet others.

Using certain medicines can make it more difficult for one to tell when you might have low blood glucose levels. Tell your physician if you use any of these:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers for example atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), yet others.

You may be prone to have hyperglycemia (high blood sugar) in the event you take glyburide with:

isoniazid;

diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine while others);

thyroid medicine (Synthroid yet others);

birth control pills along with other hormones;

heart or hypertension medications (Cartia, Cardizem, Nifedical, Covera, Verelan, while others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, while others);

seizure medicines (Dilantin and others); and

diet pills or medicines to take care of asthma, colds or allergies.


You could be more prone to have hypoglycemia (low blood sugar levels) if you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or hypertension medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, among others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin and other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, yet others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists usually are not complete and there are many other medicines that may increase or minimizing the effects of glyburide on cutting your blood sugar. Tell your medical professional about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your doctor.

 

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