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Precautions

It is critical that your physician check your progress at regular visits to allow for modifications in your dose and to look for any negative effects.

Do not take selegiline if you've used meperidine (e.g., Demerol®) or even an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 2 weeks. If you do, you may develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body's temperature, higher than normal blood pressure, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you're employing this medicine. Using these medicines together might cause negative effects.

Selegiline could cause serious side effects when used in addition to some antidepressants. Tell a medical expert if you might have used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past two weeks.

When selegiline is taken at doses of 10 mg or less each day to the treatments for Parkinson's disease, there won't be any restrictions on food or beverages you eat or drink. However, the opportunity exists that dangerous reactions, like sudden high blood pressure level, may occur if doses higher than those useful for Parkinson's disease are taken with foods, beverages, or another medicines. These foods, beverages, and medicines include:

• Foods who have a high tyramine content (most frequent in foods which might be aged or fermented to improve their flavor), like cheeses; fava or broad bean pods; yeast or meat extracts; smoked or pickled meat, poultry, or fish; fermented sausage (bologna, pepperoni, salami, summer sausage) or another fermented meat; sauerkraut; or any overripe fruit. If a list of simply because and beverages isn't directed at you, ask your physician to supply one.
• Alcoholic beverages or alcohol-free or reduced-alcohol beer and wine.
• Large amounts of caffeine-containing food or beverages for example coffee, tea, cola, or chocolate.
• Any other medicine unless approved or prescribed by your doctor. This especially includes nonprescription (over-the-counter [OTC]) medicine, such as that for colds (including nose drops or sprays), cough, asthma, hay fever, and appetite control; “keep awake” products; or items that cause you to sleepy.

Also, for about two weeks after you stop taking this medicine, these foods, beverages, as well as other medicines may continue to react with selegiline whether or not this was drawn in doses greater than those usually used by Parkinson's disease.

Check with your medical professional or hospital er immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you might be using this medicine. These may be signs and symptoms of a serious side effect which will have a very doctor's attention.

Dizziness, lightheadedness, or fainting may occur, particularly when you will get up coming from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, consult your doctor.

Selegiline may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt items of ice within your mouth, or utilize a saliva substitute. However, should your mouth will continue to feel dry in excess of fourteen days, check together with your health practitioner or dentist. Continuing dryness of the mouth may increase the opportunity of dental disease, including dental cairies, gum disease, and fungus infections.

It is very important that your physician look at your skin for melanoma (tumor) regularly if you've got Parkinson's disease.

Do not stop taking this medicine without first checking with your doctor. Your doctor may want that you reduce gradually the amount you are taking before stopping completely.

Hallucinations may occur in some patients. This is more widespread with elderly patients. If you have hallucinations, seek advice from your physician.

Some individuals who have used this medicine had unusual alterations in their behavior. Talk with your medical professional in case you start experiencing difficulity with gambling or increased sexual libido while employing this medicine.