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Precautions

Do NOT use Plavix if:

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• you're allergic to the ingredient in Plavix

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• you have an active bleeding disorder, like a stomach ulcer or bleeding inside the brain

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• you consider certain azole antifungals (eg, fluconazole, ketoconazole, voriconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, certain proton pump inhibitors (eg, omeprazole, esomeprazole), or ticlopidine.

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Contact your physician or physician without delay if these affect you.

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Some medical ailments may communicate with Plavix. Tell your medical professional or pharmacist for those who have any health conditions, particularly when any in the following affect you:

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• if you're pregnant, planning to become pregnant, or are breast-feeding

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• when you have allergies to medicines, foods, or any other substances

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• for those who have bone marrow disease, liver or kidney problems, or a reputation ulcers

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• for those who have had a recent injury or surgery, including dental surgery.

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Some medicines may interact with Plavix. Tell your doctor if you are taking every other medicines, especially any with the following:

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• Dabigatran, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oral anticoagulants (eg, warfarin), or salicylates (eg, aspirin) since the probability of bleeding might be increased by Plavix

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• Azole antifungals (eg, ketoconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, proton pump inhibitors (eg, omeprazole), or ticlopidine given that they may decrease Plavix's effectiveness

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• Fluvastatin, phenytoin, tamoxifen, tolbutamide, or torsemide as the probability of their unwanted side effects could be increased by Plavix.

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This will not be a complete list of all interactions that could occur. Ask your health care provider if Plavix may communicate with other medicines that you just take. Check with your health care provider before you begin, stop, or change the dose associated with a medicine.

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Important safety information:

• Plavix may cause dizziness. This effect may be worse if you go on it with alcohol or certain medicines. Use Plavix with caution. Do not drive or perform other possible unsafe tasks unless you know how you respond to it.

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• Plavix may decrease the amount of clot-forming cells (platelets) within your blood. Avoid activities that might cause bruising or injury. Tell your doctor in case you have unusual bruising or bleeding. Tell your physician if you have dark, tarry, or bloody stools.

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• Tell your doctor or dentist that you take Plavix prior to deciding to get any medical or dentistry, emergency care, or surgery. You may need to stop Plavix before you've got certain kinds of surgery.

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• Plavix should be converted inside the body for it to operate. This conversion does not occur at the same time in some people (about 2% of white patients, 4% of black patients, and 14% of Chinese patients). The medicine might not exactly work too of these patients. Your doctor may carry out a test to check on how well one's body is able to convert Plavix. Talk together with your doctor for more info.

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• Plavix shouldn't be utilized in children; safety and effectiveness in youngsters are not confirmed.

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• Pregnancy and breast-feeding: If you think you may be pregnant, contact your doctor. You will need to discuss the rewards and perils associated with using Plavix while you're pregnant. It is not known if Plavix is located in breast milk. Do not breastfeed while taking Plavix.

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