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Precautions

Do NOT use Crestor if:

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• you have liver problems or unexplained abnormal liver function tests

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• you're pregnant or breast-feeding

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• you take itraconazole, mibefradil, or telithromycin.

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Contact a medical expert or doctor straight away if these affect you.

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Some health conditions may communicate with Crestor. Tell your physician or pharmacist in case you have any health conditions, particularly if any from the following affect you:

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• if you're planning to become pregnant

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• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• for those who have allergies to medicines, foods, or any other substances

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• if you have low hypertension, a serious infection, kidney problems, an underactive thyroid, diabetes, or a history of seizures

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• if you're dehydrated or have certain muscle problems (eg, pain, weakness); have raised creatine phosphokinase (CPK) blood levels; or have metabolism, hormonal, or electrolyte problems

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• if you might be on dialysis

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Some medicines may communicate with Crestor. Tell your doctor if you consider another medicines, especially any of the following:

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• Fibrates (eg, gemfibrozil, clofibrate), immunosuppressants (eg, cyclosporine), lopinavir/ritonavir, or niacin because they might increase the risk of muscle or kidney problems

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• Anticoagulants (eg, warfarin), cimetidine, ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone for the reason that probability of their unwanted effects might be increased by Crestor.

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This may not be a total report on all interactions that may occur. Ask your health care provider if Crestor may connect to other medicines that you just take. Check with your medical provider prior to starting, stop, or change the dose of any medicine.

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Important safety information:

• Crestor could cause dizziness. These effects could possibly be worse if you take it with alcohol or certain medicines. Use Crestor with caution. Do not drive or perform other possible unsafe tasks before you recognize how you react to it.

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• Drinking alcohol daily or even in huge amounts might increase the likelihood of liver issues with Crestor. Check with your medical professional before alcohol consumption as you take Crestor.

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• Follow the diet and use program presented to you through your health care provider.

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• Lab tests, including blood cholesterol, liver function, kidney function, and creatine phosphokinase (CPK) blood levels, may be performed when you use Crestor. These tests might be utilized to monitor your complaint or search for side effects. Be sure to keep all doctor and lab appointments.

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• Use Crestor with caution in Asian patients and elderly patients; they might be more understanding of its effects, especially serious muscle problems (eg, muscle pain, tenderness, or weakness).

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• Crestor needs to be used with careful attention in kids; safety and effectiveness in kids are not confirmed.

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• Pregnancy and breast-feeding: Do not use Crestor if you happen to be pregnant. It could potentially cause harm to the fetus. Avoid pregnancy whilst you are taking it. If you think you could possibly be pregnant, contact your medical professional without delay. It is not known if Crestor is found in breast milk. Do not breastfeed while taking Crestor.

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