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Uses

INDICATIONS

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Keppra is utilized to treat partial onset seizures in older adults and youngsters who are no less than 30 days old.
It is additionally used to take care of tonic-clonic seizures in adults and kids who are at the very least 6 years of age, and myoclonic seizures in grown-ups and youngsters that are a minimum of 12 yrs . old.

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INSTRUCTIONS

Take Keppra the same manner prescribed through your doctor. Do not take in larger or smaller amounts and for longer than recommended. Follow the directions on your own prescription label.

Your doctor may occasionally alter your dose to make sure you receive the best results.

Keppra is normally taken twice every day. Take the medicine at the same time each day. You may take Keppra with or without food.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not having a regular table spoon. If you do not possess a dose-measuring device, ask the pharmacist for one.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause too much of the drug to be sold previously.

Use Keppra regularly to obtain the most benefit. Get your prescription refilled before you decide to run out of medicine completely.

Do not stop using Keppra without first actually talking to your doctor, even if you feel fine. You could have increased seizures in case you stop using this medicine suddenly. You should use less and less when you stop the medication completely.

Seizures tend to be treated with a combination of different drugs. Use all medications as directed from your doctor. Read the medication guide or patient instructions furnished with each medication. Do not improve your doses or medication schedule without a medical expert's advice. .

Wear a medical alert tag or carry an ID card stating that you take Keppra. Any medical treatment provider who treats you need to understand that you are taking seizure medication.

To be sure Keppra isn't causing harmful effects, your kidney function should be tested. Visit your physician regularly.

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If you missed a dose - consider the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to produce in the missed dose.

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DOSAGE

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Important Administration Instructions

Keppra is offered orally with or without food. The Keppra dosing regimen depends upon the indication, generation, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with bodyweight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with weight above 20 kg.

When while using the oral solution in pediatric patients, dosing is weight-based (mg per kg) by using a calibrated measuring device (not only a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets mustn't be chewed or crushed.

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Pediatric Patients

Treatment ought to be initiated which has a daily dose of 14 mg/kg in 2 divided doses (7 mg/kg twice a day). The daily dose ought to be increased every 2 weeks by increments of 14 mg/kg towards the recommended daily dose of 42 mg/kg (21 mg/kg twice daily). In the medical trial, the mean daily dose was 35 mg/kg within this age group. The effectiveness of lower doses will not be studied.

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Treatment ought to be initiated which has a daily dose of 20 mg/kg into two divided doses (10 mg/kg twice a day). The daily dose ought to be increased into two weeks by an increment of 20 mg/kg to the recommended daily dose of 50 mg/kg (25 mg/kg twice a day). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose might be reduced. In the medical trial, the mean daily dose was 47 mg/kg on this age bracket.

Treatment needs to be initiated which has a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg twice a day). The daily dose must be increased every 14 days by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). If a patient cannot tolerate a daily dose of 60 mg/kg, the daily dose could possibly be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment should be initiated having a daily dose of 500 mg given as twice daily dosing (250 mg two tmes a day). The daily dose ought to be increased every fourteen days by increments of 500 mg to a maximum recommended daily dose of 1500 mg (750 mg two tmes a day).

For Keppra tablet dosing in pediatric patients weighing a lot more than 40 kg, treatment should be initiated using a daily dose of 1000 mg/day given as twice daily dosing (500 mg two tmes a day). The daily dose needs to be increased every fourteen days by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg two tmes a day).

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Partial Onset Seizures
Adults 16 Years And Older

In many studies, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were confirmed to be effective. Although in some studies there was an inclination toward greater response with higher dose [see Clinical Studies], a frequent rise in response to comprehend dose has not been shown.

Treatment needs to be initiated having a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Additional dosing increments may be given (1000 mg/day additional every fourteen days) to your maximum recommended daily dose of 3000 mg. Doses more than 3000 mg/day are actually found in open-label studies for periods of six months and longer. There is no evidence that doses more than 3000 mg/day confer additional benefit.

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Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment should be initiated which has a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage must be increased by 1000 mg/day every two weeks to the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day will not be studied.

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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment ought to be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage must be increased by 1000 mg/day every 14 days towards the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day has not been adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment should be initiated which has a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg two tmes a day). The daily dose needs to be increased every 2 weeks by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). The effectiveness of doses below 60 mg/kg/day is not adequately studied. Patients with body weight ≤ 20 kg should be dosed with oral solution. Patients with weight above 20 kg might be dosed with either tablets or oral solution. Only whole tablets should be administered.


Adult Patients With Impaired Renal Function
Keppra dosing have to be individualized according for the patient's renal function status.

STORAGE

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Store Keppra at room temperature away from moisture, heat, and light-weight.

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Side Effects

Get emergency medical help if you have any of these signs and symptoms of a hypersensitive reaction to Keppra: hives; difficult breathing; swelling of the face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, including: mood or behavior changes, depression, anxiety, or should you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor immediately in the event you have a serious complication including:

Less serious Keppra side effects can sometimes include:

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This is not a complete list of unwanted effects while others may occur. Tell a medical expert about any unusual or bothersome side effect.

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Precautions

You should not use Keppra in the event you are allergic to levetiracetam.

To make sure you can safely take Keppra, tell a medical expert in the event you have kidney disease or hypertension.

You could possibly have thoughts about suicide while using this medicine. Tell your doctor in case you have symptoms of depression or suicidal thoughts throughout the first a few months of treatment, or once your dose is changed.

Your family or any other caregivers should also be tuned in to changes with your mood or symptoms. Your doctor should check you at regular visits.

FDA pregnancy category C. It isn't known whether Keppra will harm an child, but having a seizure in pregnancy could harm the two mother and also the baby. Tell your medical professional if you are pregnant or intend to conceive while using this medication. Do not start or stop taking Keppra while pregnant without your medical professional's advice. Seizure control is very important when pregnant. The benefit of preventing seizures may outweigh any risks resulting from taking Keppra. Follow a medical expert's instructions about taking Keppra while you are pregnant. Levetiracetam can pass into breast milk and could harm a nursing baby. You should not breast-feed if you are using Keppra. Do not give medicines to some child without the advice of an doctor. Your child's dose needs derive from age and weight. The child should remain under the care of your doctor while using this medicine.

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Do not stop using Keppra without first speaking with a medical expert, although you may feel great. You might have increased seizures if you stop using Keppra suddenly. You should use less and less before you stop the medication completely.

You could have thoughts about suicide while taking Keppra. Your doctor should check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to a medical expert, for example: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card stating that you are taking Keppra. Any medical treatment provider who treats you need to understand that you take seizure medication.

Keppra may impair your notions or reactions. Be careful in the event you drive or do anything whatsoever that needs you to be alert. Tell your doctor in case you are pregnant or plan to get pregnant while applying this medication. Do not start or stop taking Keppra during pregnancy without your doctor's advice. Having a seizure when pregnant could harm the two mother and also the baby. Seizure control is vital in pregnancy along with the advantages of preventing seizures may outweigh any risks presented by using Keppra.

Avoid having a drink. It can increase a number of the unwanted effects of Keppra and could also increase the potential risk of seizures. This medication may impair your opinions or reactions. Be careful in the event you drive or a single thing that needs one to be alert.

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