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Precautions

Do NOT use Estrace if:

• you are allergic to the ingredient in Estrace
• you are pregnant or suspect you may be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause
• you've known or suspected breast cancers (unless directed from your doctor) otherwise you have cancers that are estrogen-dependent
• you might have blood clots, vein inflammation, or liver disease
• you experienced a newly released stroke or heart attack.

Contact your doctor or health care provider without delay if some of these apply to you.

Some health concerns may connect to Estrace. Tell your medical professional or pharmacist in case you have any health concerns, especially if any from the following sign up for you:

• in case you are planning to become pregnant
• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• in case you have allergies to medicines, foods, or other substances
• in case you have a genealogy and family history of cancer of the breast, or you have breast lumps or disease, or even an abnormal mammogram
• in case you have yellowing of the whites from the eyes or skin while pregnant or with past estrogen use, or hypertension when pregnant (toxemia)
• in case you have a vaginal infection or womb problems (eg, uterine fibroids/endometriosis, abnormal vaginal bleeding, other uterine problems)
• when you have abnormal calcium levels within the blood, asthma, cancer, certain blood disorder (porphyria), cholesterol or lipid problems, depression, diabetes, epilepsy, excessive extra weight, gallbladder disease, cardiovascular disease or any other heart disease, high blood pressure, kidney or liver disease, low thyroid hormonal changes, lupus, headaches, pancreas disease, seizures, or yellowing from the skin or eyes
• in the event you smoke or will probably be having surgery.

Some medicines may talk with Estrace. Tell your health care provider if you're taking some other medicines, especially any in the following:

• Blood thinners (eg, warfarin), corticosteroids (eg, prednisone), succinylcholine, or tacrine as their actions and the likelihood of their unwanted effects could possibly be increased by Estrace
• Blood thinners (eg, warfarin) because their effectiveness may be decreased by Estrace
• Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or rifampin simply because they may decrease Estrace's effectiveness.

This may not be an entire listing of all interactions that will occur. Ask your health care provider if Estrace may communicate with other medicines which you take. Check with your medical provider prior to starting, stop, or alter the dose associated with a medicine.

Important safety information:

• Estrace could cause dizziness. This effect may be worse in the event you take it with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possible unsafe tasks unless you understand how you react to it.
• Limit alcohol based drinks if you are taking Estrace.
• Estrace could potentially cause dark skin patches on your face (melasma). Exposure for the sun will make these patches darker and you'll must avoid prolonged sun damage and sunlamps. Consult your physician regarding the use of sunscreens and protective clothing.
• Estrace could raise the risk of blood clots. The risk might be greater if you smoke (especially in women older than 35 yrs . old).
• Contact your medical professional if vaginal bleeding of unknown cause occurs. This could be a sign of a critical condition requiring immediate medical help.
• Contact your doctor if vaginal discomfort occurs or should you suspect you have developed an infection while taking Estrace.
• Follow a medical expert's instructions for examining your breasts and report any lumps immediately.
• Additional monitoring of your dose or condition could be necessary in case you are presently taking an azole antifungal (eg, itraconazole), carbamazepine, a macrolide antibiotic (eg, erythromycin), ritonavir, cimetidine, or St. John's wort.
• If you wear disposable lenses and you develop issues with them, get hold of your doctor.
• If you will likely be having surgery or is going to be restricted to a chair or bed for some time of your energy (eg, an extended plane flight), notify a medical expert beforehand. Special precautions may must be taken in these circumstances when you are taking Estrace.
• Nonprescription therapy to aid prevent bone loss includes a weight-bearing exercise program, as well as adequate daily calcium and vitamin D intake. Consult your medical professional or pharmacist for more details.
• Some of such products might have the dye tartrazine (FD&C Yellow No. 5), which may cause allergies using patients. Consult your medical professional or pharmacist. If you previously had allergic reactions for the dye tartrazine, get hold of your doctor or pharmacist to find out if your product you are taking offers the dye tartrazine.
• Estrace may interfere with certain tests. Be sure a medical expert and lab personnel know you're taking Estrace.
• Diabetes patients - Estrace may affect your blood sugar. Check blood glucose levels closely. Ask your physician before you decide to change the dose of your diabetes medicine.
• Lab tests, including physical exams and hypertension, may be performed whilst you use Estrace. You should have breast and pelvic exams, and a Pap test one or more times annually. You should also have periodic mammograms as determined from your doctor. Be sure to keep all doctor and lab appointments.
• Estrace should not be found in children; safety and effectiveness in children are not confirmed.
• Pregnancy and breast-feeding: Do not use Estrace if you are pregnant. Avoid pregnancy while you are taking it. If you think you might be pregnant, speak to your doctor without delay. Estrace could possibly be found in breast milk. If you are or will be breast-feeding while you use Estrace, check with your doctor. Discuss any possible risks in your baby.