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Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.

This medication belongs to a course of medications called tricyclic antidepressants. It works by restoring the balance of certain substances that are naturalserotonin, and others) in the brain.

OTHER USES: This section contains uses of the medication which are maybe not placed in the approved professional labeling for the drug but that may be prescribed by the medical care professional. Use this drug for a condition that is listed in this part only if it was so prescribed by your health care professional.

This medication has additionally been used to treat depression, panic assaults, and pain that is ongoing.

How exactly to use Anafranil

Read the Medication Guide available from your pharmacist. Consult your pharmacist or doctor if you have any questions.

Take this medication by mouth with or without meals as directed by your physician. To lessen negative effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Usually, the daily dose will maybe not be more than 250 milligrams for adults and 200 milligrams for kids and teenagers.

Follow your medical practitioner's directions carefully. Never take just about medication or take it more frequently than prescribed. Your condition shall not improve any faster and your risk of adverse results such as for example seizures may be increased. Dosage is based on your medical condition and response to therapy.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more details.

Make use of this medication regularly in order to obtain the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the time( that is same) each time.

Never suddenly stop using this medication without consulting your medical professional. Some conditions may be even worse when the drug is abruptly stopped. You may possibly experience sweating, dizziness, sickness, vomiting, headache, or irritability if you suddenly stop taking this drug. Your dose may gradually need to be decreased.

It may just take 2 to 3 months or longer ahead of the full ramifications of this medication are noticed. Inform your doctor if the condition persists or if it worsens.

adverse Effects

See also Warning section.

Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety signs may temporarily worsen when you initially start clomipramine that is taking. If any of these effects persist or worsen, notify your pharmacist or doctor immediately.

To alleviate mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or utilize a saliva substitute.

To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. If you feel constipated while by using this drug, check with your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).

Understand that your physician has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

Tell your doctor right away if some of these unlikely but side that is serious occur: mental/mood modifications (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk production, irregular/painful menstrual durations, muscle tissue stiffness, ringing within the ears, sexual dilemmas (e.g., decreased sexual ability, alterations in desire), shakiness (tremors), numbness/tingling for the hands/feet, difficulty urinating.

Tell your physician right away if any of these rare but very adverse that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled motions (especially regarding the tongue/face/lips), serious stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and hardly ever cause a very condition that is serious serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop a few of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, uncommon agitation/restlessness.

Get medical help right away if you have any very serious part effects, including: black stools, chest discomfort, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights through the night).

A tremendously serious reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially associated with the face/tongue/throat), severe dizziness, trouble breathing.

This is not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Phone your physician for medical advice about adverse effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical professional for medical advice about side effects. You may report adverse effects to Health Canada at 1-866-234-2345.


Before taking clomipramine, tell your physician or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergic reactions or other issues. Confer with your pharmacist for more information.

Before applying this medicine, tell your doctor or pharmacist your medical history, especially of: blood dilemmas (e.g., purpura, thrombocytopenia), difficulty in breathing (age.g., asthma, chronic bronchitis), personal or genealogy of glaucoma (angle-closure type), eating disorders (e.g., bulimia), heart issues (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal problems (e.g., chronic constipation, ileus), liver problems, kidney dilemmas, personal or genealogy and family history of other mental/mood conditions (e.g., manic depression, schizophrenia), history of hospitalization for a very serious reaction to specific medicines (neuroleptic cancerous problem), heartburn/stomach acid within the esophagus (age.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may boost your risk of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive treatment, mind injury/disease), certain kinds of tumors (e.g., pheochromocytoma, neuroblastoma).

Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can hardly ever cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention immediately.

The danger of QT prolongation may be increased in the event that you have actually certain conditions that are medical are taking other drugs that could cause QT prolongation. Before using clomipramine, inform your medical professional or pharmacist of all of the drugs you are taking and in case you have any one of the next conditions: certain heart related illnesses (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Lower levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Talk to your physician about making use of clomipramine safely.

This drug could make you dizzy or drowsy or cause temporary vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

To diminish dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Before having surgery, tell your dentist or doctor that you are taking this medication.

Caution is advised when working with this medication in kids whom take part in active activities because it may increase the risk of heart problems. (See also the Warning section.)

Older grownups may be more sensitive to the relative negative effects of the medication, especially bleeding, confusion, dizziness, and QT prolongation (see above).

This medication should be used only when demonstrably needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or unwanted effects. Inform your doctor straight away in the event that you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.

Since untreated mental/mood problems (such as for instance obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medication passes into breast milk and may even have undesirable effects on a nursing baby. Consult with your doctor before breast-feeding.

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