Methotrexate can be used to treat certain types of cancer or to control psoriasis that is severe rheumatoid arthritis that has not responded to other treatments. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system.
Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to lessen further joint harm and to preserve function that is joint.
OTHER USES: This section contains uses of this medication which are not placed in the approved labeling that is professional the drug but which will be prescribed by your health care pro. Utilize this drug for a condition that is listed in this section only if it has been therefore prescribed by your medical care professional.
This medicine doubles for lupus and arthritis that is psoriatic.
Read the Patient Information Leaflet if available from your pharmacist you get a refill before you start taking methotrexate and each time. If you have any relevant questions, ask your doctor or pharmacist.
Methotrexate is a strong medication. The dosage and how often you take this medication are based on your condition that is medical and to treatment. There are many different dosing schedules for this medication (especially for cancer treatment). Therefore, it is vital that you follow your medical professional's guidelines carefully. Take this medicine by lips as directed by the doctor.
For the treating psoriasis or rheumatoid arthritis, simply take this medication by mouth as directed by your doctor, usually once a week. It could take around several months before you have the benefit that is full of drug.
Usually do not increase your dose or use this drug more often or for longer than prescribed. Your condition shall not improve any faster, and your risk of negative effects will increase.
Since this drug are consumed through skin and lung area and may also harm an baby that is unborn ladies who are pregnant or who may conceive should not handle this medicine or breathe the dirt through the pills.
Drink plenty of liquids while taking this medication unless your physician tells you otherwise. Doing this helps your kidneys to eliminate the medication from the human body and steer clear of some of the relative unwanted effects.
See also Warning section.
Nausea, sickness, stomach pain, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your pharmacist or doctor promptly.
Temporary hair loss might occur. Normal hair regrowth should return after therapy has ended.
Remember that the doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious side effects.
Tell your doctor right away in the event that you have serious adverse effects, including: mouth sores, diarrhea, signs of anemia (such as for example unusual tiredness, pale skin), signs of liver issues (such as dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone tissue pain, unusual discomfort and discoloration of skin, change in the quantity of urine, dry cough, muscle weakness.
Get medical help right away if you have got any very severe side effects, including: weakness on one part associated with body, neck stiffness, serious frustration, eyesight changes, irregular heartbeat, mental/mood changes, seizures.
This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent throat that is sore cough).
This medication can impact sperm production, an impact that may lower fertility that is male. Check with your doctor for lots more details.
A very severe reaction that is allergic this drug is rare. However, get medical help right away in the event that you notice any symptoms of a serious hypersensitive reaction, including: rash, itching/swelling (especially associated with face/tongue/throat), severe dizziness, difficulty breathing.
This is not a complete list of possible adverse effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In the US -
Call your medical professional for medical advice about side-effects. You could report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about negative effects. You may report side effects to wellness Canada at 1-866-234-2345.
See section that is also warning.
Before taking methotrexate, tell your medical professional or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which could cause allergic responses or other problems. Confer with your pharmacist for more details.
Before applying this medication, inform your doctor or pharmacist your medical history, especially of: liver condition, kidney illness, lung disease (such as for instance pulmonary fibrosis), liquor usage, suppressed immune system, blood cell/bone marrow problems, stomach/intestinal diseases (such as for example peptic ulcer, ulcerative colitis), any active illness (including chickenpox or current exposure to it), folic acid deficiency.
Methotrexate can make you more likely to get infections or may worsen any infections that are current. Therefore, wash the hands well to prevent the spread of infection. Avoid contact with those who have infections that may spread to others (such as chickenpox, measles, flu). Consult your physician for those who have been subjected to an infection or even for more details.
Don't have immunizations/vaccinations without the consent of your doctor. Prevent experience of people who have recently received vaccines that are livesuch as for example flu vaccine inhaled through the nose).
To lower the chance of getting cut, bruised, or injured, use caution with razor-sharp objects like razors and nail cutters, and avoid activities such as for instance contact sports.
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Avoid beverages that are alcoholic.
Before having surgery, tell your medical professional or dentist about all these products you employ (including prescription drugs, nonprescription drugs, and herbal products).
This medication might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Methotrexate must not be utilized during maternity. It might probably harm an baby that is unborn. It is important to prevent pregnancy during and after treatment with methotrexate. Therefore, males and females must use reliable forms of birth control (such as condoms, birth control pills) during treatment. Males should continue to use birth control for at least 3 months after the final end of treatment. Females should continue to use contraception for at minimum 1 menstrual cycle after the end of treatment. If you become pregnant or think you may be pregnant, tell your doctor right away.
Since this drug can be consumed through the skin and lungs and may harm an unborn baby, women who're pregnant or who may get pregnant should not manage this medication or inhale the dust from the tablets.
Methotrexate passes into breast milk and may harm a medical infant. Therefore, breast-feeding when using this drug isn't recommended. Consult your physician before breast-feeding.
Airmail: 2-3 business weeks, EMS: 3-8 business days.
Airmail: 2-3 business weeks, EMS: 3-8 business days.