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See section that is also warning.

Promethazine is employed to prevent and treat sickness and vomiting associated to conditions that are certainsuch as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and nose that is runny. It may possibly be used to assist you feel sleepy/relaxed before and after surgery or to assist certain pain that is narcotic (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the cold that is common.

Promethazine is an antihistamine and works by blocking a certain normal substance (histamine) that your body makes during an reaction that is allergic. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other substances that are naturalsuch as acetylcholine) and also by acting entirely on certain parts of the mind.

Cough-and-cold products haven't been been shown to be effective or safe in children younger than 6 years. Therefore, do not use this product to treat symptoms that are cold children younger than 6 years unless specifically directed by the physician. Some products (such as long-acting tablets/capsules) are not advised for use in kids younger than 12 years. Pose a question to your doctor or pharmacist for lots more details about utilizing your product safely.

These products do perhaps not cure or shorten the size of the common cold and may cause serious side effects. To decrease the risk for serious adverse effects, follow all dosage carefully instructions. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use promethazine

Read the Patient Suggestions Leaflet if available from your pharmacist before you start taking promethazine and each time you get a refill. If you have any relevant questions, ask your physician or pharmacist.

Take this medication by lips with or without meals as directed by the doctor, usually 2 to 4 times daily. For motion sickness, the first dose of promethazine should be taken 30 to 60 minutes before beginning travel. For allergies, this medication may be taken once daily at bedtime to avoid being drowsy during the day. When used before surgery, promethazine may be taken the night before or just before the procedure and may be continued afterwards as directed.

If you are using the liquid form of this medication, carefully determine the dosage using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on how old you are, medical condition, and reaction to treatment. In children, the dosage might also be based on fat. Do not increase your dosage or simply take this medicine more often than directed.

Tell your medical practitioner in case your condition does not enhance or if it worsens.

What conditions does promethazine treat?

Negative Effects

Drowsiness, dizziness, constipation, blurred vision, or mouth that is dry happen. If any of these results persist or aggravate, inform your physician.

To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or make use of a saliva replacement.

Remember that your medical practitioner has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have side that is serious.

Tell your physician appropriate away if you have any serious negative effects, including: fainting, slow heartbeat, mental/mood changes (such as hallucinations, nervousness, irritability, restlessness, confusion), unusual/uncontrolled motions (such as fixed upward stare, neck twisting, tongue movements), shaking (tremor), difficulty urinating, simple bleeding/bruising, indications of illness (such as fever, persistent sore throat), severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin.

Get medical help right away if you have any very serious side-effects, including: slow/shallow breathing, seizures.

This medication may seldom cause an extremely serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away when you have some of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, improvement in the quantity of urine.

A tremendously severe allergic reaction to this drug is rare. However, get help that is medical away if you see any observeable symptoms of a significant hypersensitive reaction, including: rash, itching/swelling (especially associated with face/tongue/throat), severe dizziness, trouble respiration.

This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your physician for medical advice about adverse effects. You could report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about adverse effects. You may report effects that are side wellness Canada at 1-866-234-2345.

List side that is promethazine by likelihood and severity.


See section that is also warning.

Before taking promethazine, inform your physician or pharmacist in the event that you are allergic to it; or to any other phenothiazines (such as prochlorperazine); or if you have any other allergies. This product may contain inactive ingredients, which causes allergies or other problems. Speak to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic obstructive pulmonary disease-COPD, sleep apnea), blood/immune system problems (such as bone marrow despair), high stress into the eye (glaucoma), heart disease (such as irregular heartbeat), high blood pressure, liver disease, certain brain disorders (such as neuroleptic malignant problem, Reye's syndrome, seizures), stomach/intestine problems (such as for instance obstruction, ulcer), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Avoid beverages that are alcoholic.

Before having surgery, tell your medical professional or dentist about all of the products you use (including prescription drugs, nonprescription drugs, and natural products).

Promethazine may make you more sensitive to your sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when in the open air.

This medicine may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using tubs that are hot. When the weather is hot, take in a complete lot of fluids and dress lightly. If you overheat, quickly look for a accepted place to cool down and rest. Get help that is medical away if you have a fever that does not go away, mental/mood changes, headache, or dizziness.

Fluid products may include sugar and/or alcohol. Caution is advised if you have diabetes, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about making use of this product safely.

Young ones may be more responsive to the unwanted effects of this medication, particularly slowed breathing (see Warning part). This medication can cause excitement in often young children instead of drowsiness. Special care should be taken when using this medication in children who have lost a complete lot of fluid (dehydration), those who have actually a household reputation for sudden infant death syndrome (SIDS), and those who find themselves difficult to wake up from sleep.

Older adults may be more delicate to the relative side ramifications of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can raise the risk of falling.

During pregnancy, this medication should be properly used just when obviously needed. Talk about the risks and advantages with your physician.

It is unknown if promethazine passes into breast milk. It may have effects that are undesirable a nursing infant. Consult your doctor before breast-feeding.

What should I understand regarding pregnancy, medical and administering promethazine to children or the elderly?

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