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This medication is utilized to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, better help you sleep, and increase your power level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain chemicals that are naturalneurotransmitters such as for instance serotonin) within the brain.

OTHER USES: This section contains uses with this medication that are not placed in the approved labeling that is professional the medication but that could be recommended by your wellbeing care professional. Utilize this drug for a condition that is listed in this section just if it is often so prescribed by your medical care professional.

This medicine may also be used to treat neurological discomfort (such as peripheral neuropathy, postherpetic neuralgia), eating disorder (bulimia), other mental/mood problems (such as anxiety, panic disorder), or to prevent migraine headaches.

Exactly how to use Endep

Read the Medication Guide provided by your pharmacist you get a refill before you start taking amitriptyline and each time. If you have any relevant concerns, consult your physician or pharmacist.

Take this medicine by mouth, frequently 1 to 4 times daily or as directed by your medical professional. If you take it only once a day, take it at bedtime to help reduce daytime sleepiness. The dosage is based on your medical condition and response to therapy.

To reduce your risk of side results (such as for instance drowsiness, dry lips, dizziness), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your medical practitioner's instructions carefully.

Take this medication regularly to be able to obtain the most benefit from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or use this drug more frequently or even for longer than prescribed. Your problem shall not improve any faster, and your threat of side results will increase.

You should continue taking this medication also in the event that you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may be worse whenever this drug is abruptly stopped. Also, you might experience symptoms such as mood swings, headache, tiredness, and sleep change. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist to get more details. Report any new or symptoms that are worsening away.

This medication may not away work right. You may see some benefit within a week. However, it may take up to 4 weeks before you feel the effect that is full.

Tell your doctor if your condition persists or worsens (such as your feelings of sadness worsen, or perhaps you have thoughts of committing suicide).

Part Results

See also Warning section.

Drowsiness, dizziness, dry lips, blurred vision, constipation, weight gain, or trouble urinating may occur. If any of these effects persist or worsen, notify your doctor or pharmacist immediately.

To reduce the danger of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

To alleviate dry mouth, suck on (sugarless) difficult candy or ice chips, chew (sugarless) gum, take in water, or utilize a saliva substitute.

To avoid constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. If you become constipated while applying this drug, consult your pharmacist for help in selecting a laxative.

Keep in mind that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have side that is serious.

Tell your doctor right away if any among these rare but serious side effects occur: easy bruising/bleeding, persistent heartburn, shaking, mask-like facial expressions, muscle spasms, severe stomach/abdominal pain, decreased sexual ability/desire, enlarged/painful breasts.

Get help that is medical away in the event that you have actually any very serious adverse effects, including: black stools, vomit that looks like coffee grounds, serious dizziness, fainting, seizures, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights at night).

This medication may rarely cause a very condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms: fever, muscle mass stiffness, severe confusion, perspiring, fast/irregular heartbeat.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a significant hypersensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty respiration.

This is not a list that is complete of side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Within the US -

Call your doctor for medical advice about adverse impacts. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about adverse effects. You may report effects that are side Health Canada at 1-866-234-2345.


See section that is also warning.

Before taking amitriptyline, inform your doctor or pharmacist in the event that you have any other allergies if you are allergic to it, or to other tricyclic antidepressants (such as nortriptyline), or. This product may contain inactive ingredients, which could cause allergic reactions or other dilemmas. Talk to your pharmacist for more details.

Before using this medicine, tell your medical practitioner or pharmacist your medical history, especially of: bleeding problems, breathing problems, liver problems, recent heart assault, problems urinating (such as due to enlarged prostate), overactive thyroid (hyperthyroidism), personal or family history of glaucoma (angle-closure type), personal or genealogy and family history of mental/mood conditions (such as bipolar disorder, psychosis), household history of suicide, seizures, conditions that could increase your danger of seizures (such as other brain infection, alcohol withdrawal).

Amitriptyline may cause an ailment that affects the center rhythm (QT prolongation). QT prolongation can hardly ever cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical help right away.

The possibility of QT prolongation may be increased if you have specific medical conditions or are using other drugs that may cause QT prolongation. Before making use of amitriptyline, tell your doctor or pharmacist of all the drugs you take and in the event that you have some of the following conditions: certain heart problems (heart failure, sluggish heartbeat, QT prolongation within the EKG), household history of specific heart disease (QT prolongation in the EKG, sudden cardiac death).

Low degrees of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Confer with your doctor about using amitriptyline safely.

This drug may make you drowsy or dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Avoid beverages that are alcoholic.

Before having surgery, tell your doctor or dental practitioner about all the services and products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when out-of-doors.

It harder to control your blood sugar levels if you have diabetes, this drug may make. Monitor your blood sugar levels regularly and tell your doctor of the results. Your doctor might require to adjust your diabetes medication, exercise program, or diet.

Older grownups may become more responsive to the side effects of this medication, specially dry mouth, dizziness, drowsiness, confusion, constipation, difficulty urinating, and QT prolongation (see above). Dizziness, drowsiness, and confusion can boost the risk of falling.

During pregnancy, this medication should be utilized only when clearly required. Discuss the risks and benefits with your physician.

Since untreated mental/mood issues (such as depression, anxiety, panic disorder) can be a condition that is serious do not stop using this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medication passes into breast milk and the consequence on a nursing infant is unknown. Check with your doctor before breast-feeding.

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