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Uses

INDICATIONS

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Meldonium treats heart ischemia as well as consequencesis.  It is utilized in the treating brain circulation disorders. Meldonium is considered to boost Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium principal purpose is to boost Athletic Training & Competitive Performance also as microcirculation & Oxygen Delivery.

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Due to its unique mechanism of action Mildronate, according to the prescribed dose, is popular for the treatment of different heart and vascular diseases, also as for that improvement of training capacity of healthy people at physical and mental overloads and during rehabilitation period.

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INSTRUCTIONS

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Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g per day
divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, treatments is repeated in 2-3 weeks.

• Athletes should take 500 mg – 1 g twice daily before training. Duration of
treatment during preparatory period is 2-3 weeks, throughout competition – 10-14 days.

• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) every day, taking the whole dose in the past or dividing for two takings. Course of treatment is 4-6 weeks.

• Cardialgia against the background of dyshormonal myocardiodystrophy – 500 mg per day. Course of treatment is 12 days.

• Disturbed cerebral circulation. In procedure after elimination of acute disorders: 500 mg – 1 g per day, taking the whole dose previously or dividing it for 2 takings. In case of chronic disorders: 500 mg each day. General treatment is 4-6 weeks. Recurrent courses (usually 2-3 times a year) could possibly be taken after consulting a health care provider.

• Diseases of peripheral arteries. 500 mg twice daily.

• Abstinence syndrome in the event of chronic alcoholism. 500 mg 4x each day. Course of treatment is 7-10 days.

• Maximum daily dose is 2000 mg.

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Please consult your physician just before employing this or some other vitamins and minerals or medications.

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DOSAGE

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Please consult a health care provider in connection with required dosage.

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Overdosage
There isn't any data of cases of Meldonium overdosage. The drug is low-toxic.

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STORAGE 

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Keep away from sunlight.
Keep locked and from children.
Store in dry place at room temperature.
Do not exceed storage temperature above 25 C

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Side Effects

Rarely - allergies (redness, rash, itching, oedema), at the same time as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Precautions

Contraindications:

Hypersensitivity, increased intracranial pressure (in violation from the venous outflow, intracranial tumors).

Restrictions:

Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy are not determined.

Pregnancy and breast-feeding:

Not recommended while pregnant (safety weren't proven). At the time of treatment should stop breastfeeding (known if the breast milk gets).

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Interaction with drugs as well as other kinds of interaction

The drug could be along with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible development of mild tachycardia and arterial hypotension, care needs to be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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