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Precautions

Do NOT use Coumadin if:

• you are allergic to any ingredient in Coumadin
• you've bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled blood pressure, certain blood problems (eg, low white blood cell or platelet levels), or leukemia
• you've got active serious bleeding, bleeding within the brain, certain circulation problems (eg, aneurysm, dissecting aorta), or inflammation or infection of the heart
• you might have active ulcer or bleeding from the stomach or bowel, urinary tract, genitals, or respiratory tract
• you have recently had or will be having eye, brain, or spinal cord surgery; spinal puncture; spinal anesthesia; or any type of major surgery
• you are pregnant or could become pregnant
• you cannot have routine blood clotting tests
• you are unable to follow your physician's instructions properly and never have someone that will help you take your medicine
• you consider mifepristone, streptokinase, or urokinase.

Contact your doctor or physician straight away if any of these affect you.

Some health conditions may communicate with Coumadin. Tell your physician or pharmacist in case you have any medical ailments, particularly if any in the following connect with you:

• should you be planning to become pregnant or are breast-feeding
• in case you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines or other substances
• in case you have recently been injured, fallen, given birth, or had surgery
• for those who have a good reputation for stomach or bowel obstruction (eg, bleeding, ulcer, inflammation), heart related illnesses (eg, heart failure, infection), blood clots, anemia or any other blood problems (eg, protein C deficiency, high red blood cell levels), circulation system problems, or high blood pressure levels
• in case you have a good liver, kidney, or an under active thyroid; yellowing of the skin or eyes; mental or mood problems; high cholesterol; arthritis; diabetes; or cancer
• for those who have poor nutrition, celiac disease, nutrient or fat absorption problems, or low levels of vitamin K or vitamin C within the blood, or in the event you are drinking alcoholic beverages
• if you have a fever, very poor health, diarrhea, fluid buildup, excessive fat inside the stools (steatorrhea), a recent or current infection, or tuberculosis, or in the event you will probably be subjected to high temperatures to get a prolonged duration of time
• when you have a heart valve replacement, an intrauterine device (IUD), or even a catheter.

Some medicines may connect to Coumadin. Tell your health care provider in case you are taking some other medicines, especially any in the following:

• Heparin or any other anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), salicylates (eg, aspirin), streptokinase, or urokinase for the reason that chance of bleeding may be increased
• Mifepristone because excessive bleeding may occur
• Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure levels, high-cholesterol, seizures, mental or mood problems, diabetes, stomach or bowel problems, irregular heartbeat, contraception, hormone replacement, cancer, yet others), multivitamin products, and herbal or health supplements (eg, herbals, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may communicate with Coumadin, increasing the risk of serious side effects such as bleeding or blood clots.

This is probably not a whole listing of all interactions that will occur. Ask your health care provider if Coumadin may connect to other medicines which you take. Check with your doctor before starting, stop, or alter the dose of the medicine.

Important safety information:

• Tell your medical professional or dentist that you simply take Coumadin before you get any medical or dental hygiene, emergency care, or surgery.
• Do NOT take more than the recommended dose or use for over prescribed without checking with your physician. Contact your doctor right away if you may have taken which is not Coumadin.
• Do not drink alcohol as you are taking Coumadin; it may well boost the chance of Coumadin's unwanted side effects.
• Do not change you activity level or weight without checking with your physician; the chance of Coumadin's unwanted side effects could possibly be increased.
• Do not make positive changes to eating habits without checking with your medical professional. Eat a normal, balanced diet. Foods who have high degrees of vitamin K (eg, green leafy vegetables, broccoli, liver, certain vegetable oils) may alter the effect of Coumadin. Ask your doctor for a listing of foods that could affect Coumadin. Tell your medical professional if any foods on the list really are a section of your daily diet.
• Do not eat cranberry products or drink cranberry juice as you take Coumadin. Tell a medical expert if they are actually section of your daily diet.
• Elevated body temperature may increase the effect of Coumadin. Be careful to avoid becoming overheated, especially during summer.
• Coumadin decreases blood clotting. Use caution while doing activities for example brushing your teeth, flossing, or shaving. Avoid activities that could cause bruising or injury. Seek immediate medical assistance if you fall or injure yourself. Tell a medical expert for those who have unusual bruising or bleeding. Tell your medical professional when you have dark, tarry, or bloody stools.
• Do not take aspirin when you take Coumadin unless your medical professional informs you to. If you already take aspirin for any heart or other condition, talk with your doctor about whether or not you should keep to take it with Coumadin.
• Tell a medical expert in the event you will probably be traveling or in case you will be limited to a bed or chair to get a long time period of time (eg, car or airplane ride). This may improve your risk of creating a blood clot.
• If therapy with Coumadin is stopped, the blood thinning effects may last for 2 to 5 days as soon as you stop taking it. Discuss questions or concerns with your physician. Do not suddenly stop taking Coumadin without checking with your physician.
• Lab tests, including certain blood clotting tests (eg, PT, INR), might be performed whilst you use Coumadin. These tests could be employed to monitor your trouble or check for negative effects. Be sure to keep all doctor and lab appointments.
• Use Coumadin with caution in Asian patients; they may be more understanding of its effects, especially bleeding.
• Use Coumadin with caution inside the elderly; they could possibly be more sensitive to its effects, especially bleeding.
• Coumadin must be combined with extreme care in kids; safety and effectiveness in children weren't confirmed. Children might require more frequent lab tests should they use Coumadin.
• If you can become pregnant, you need to readily effective way of contraceptive whilst you take Coumadin. If you might have questions on effective contraceptive, talk with your medical professional.
• Pregnancy and breast-feeding: Do not use Coumadin in case you are pregnant. It has been shown to harm the fetus. Avoid pregnancy while you take it. If you think you could possibly be pregnant, speak to your doctor straight away. It is not known if Coumadin is found in breast milk. If you are or is going to be breast-feeding whilst you use Coumadin, talk with your medical professional. Discuss any possible risks for your baby.