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This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing oil that is facialsebum) production. High amounts of sebum may lead to severe acne. If left untreated, severe acne may cause permanent scarring.

OTHER USES: This part contains uses of this drug being not listed in the approved labeling that is professional the drug but which will be prescribed by your health care expert. Make use of this drug for a state of being which is placed in this section only if it has been so prescribed by your health care expert.

This medicine can also be used to deal with a type that is certain of (neuroblastoma).

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Read the Medication Guide provided by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions regarding isotretinoin, consult with your medical practitioner or pharmacist before taking the medication.

Swallow capsules whole. Do not crush or chew them. Isotretinoin is frequently taken twice daily for 15-20 weeks, or as directed by your physician. Directions for many generic forms of isotretinoin state that it must be taken with dishes. Nonetheless, the FDA has indicated that the Absorica brand may be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your doctor or pharmacist for more information. Take this drug with a full glass of water, and do not lie down for 10 mins after taking it.

The dosage is founded on your condition that is medical, and reaction to treatment.

Your acne may worsen throughout the very first few days of taking this drug, plus it may use up to 1-2 months before you notice the benefit that is full of medication. If severe acne returns, a second course of treatment may be started after you have stopped taking the drug for 2 months. The manufacturer doesn't suggest long-term use of isotretinoin. Usually do not take more than the recommended dose.

Since this drug could be absorbed through the skin and lungs and may harm an baby that is unborn women who are pregnant or who may become pregnant should perhaps not manage this medication or breathe the dust from the capsules.

Unwanted Effects

Dry lips and lips, minor inflammation of the eyelids or lips, crusty skin, nosebleeds, upset belly, or thinning of locks may occur. If some of these effects persist or worsen, tell your doctor or pharmacist immediately.

To relieve dry mouth, suck on (sugarless) hard candy or ice potato chips, chew (sugarless) gum, drink water, or utilize a saliva substitute.

Keep in mind that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious adverse effects.

Tell your doctor right away in the event that you have some of these unlikely but serious side effects: mental/mood changes (e.g., depression, aggressive or violent behavior, as well as in uncommon cases, thoughts of committing suicide), tingling feeling in the skin, quick/severe sunburn (sun sensitiveness), back/joint/muscle pain, indications of disease (e.g., fever, persistent sore throat), painful swallowing, peeling epidermis on palms/soles.

Isotretinoin may rarely cause disease of the pancreas (pancreatitis) that may seldom be deadly. Stop taking this medication and inform your medical practitioner right away if you develop: severe stomach pain, severe or persistent nausea/vomiting.

Stop taking this medication and tell your doctor right away if you develop these unlikely but very serious side-effects: serious frustration, eyesight changes, ringing ears, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhoea, anal bleeding.

A very severe reaction that is allergic this drug is rare. However, seek immediate attention that is medical you notice any outward symptoms of a significant allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Phone your physician for medical advice about side effects. You may possibly report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You might report effects that are side wellness Canada at 1-866-234-2345.


Before taking isotretinoin, tell your physician or pharmacist if you have any other allergies if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergy symptoms or other dilemmas. Some individuals who are sensitive to peanuts may be allergic to also soy. Speak to your pharmacist for more details.

Anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density) before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders ( e.g..

Do not donate blood while you are taking isotretinoin and for at least 1 month after you stop taking it.

This medication might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

Isotretinoin make a difference your night vision. Do not drive, use machinery, or do any activity that requires clear vision after dark you can perform such activities safely until you are sure.

You may not tolerate them as well as usual while using this medication if you wear contact lenses. Contact your medical practitioner for more information.

Do not have cosmetic procedures to smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring may occur.

Avoid the use of alcohol while taking this medication because it might increase the risk of certain side-effects (e.g., pancreatitis).

Restricted information suggests isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop growth that is normal some children (epiphyseal dish closing). Check with your physician for more details.

Caution is preferred when making use of this medication into the elderly because they may be more painful and sensitive to its results, especially the impacts on bones.

Caution is recommended when utilizing this drug in young ones because they might be more responsive to its effects, specially back/joint/muscle pain.

This medication ought not to be utilized during maternity or by those that may become expecting during treatment. If you become pregnant or think you may be pregnant, inform your doctor right away. See section that is also warning.

Since this drug could be absorbed through the skin and lungs and may harm an baby that is unborn ladies who're pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

You must have two negative pregnancy tests before starting this medication. You must have a pregnancy that is monthly during treatment with isotretinoin. If the test is positive, you must stop taking this medication and consult your medical practitioner right away.

It is unknown if this medication passes into breast milk. However, similar medications pass into breast milk. Breast-feeding while using this medication is not advised. Consult your doctor before breast-feeding.

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