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This medicine is used alone or with other medications to prevent vomiting and nausea caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat vomiting and nausea after surgery. It works by blocking one of the body's normal substances (serotonin) that causes nausea.

How to make use of Zofran

To prevent nausea from chemotherapy, take this medication by lips usually within thirty minutes before therapy begins. To avoid nausea from radiation treatment, take this medication by lips one to two hours before the begin of your therapy. To prevent nausea after surgery, take ondansetron by mouth an hour before the beginning of surgery. This medicine might be taken with or without food. However, your doctor may tell you not to consume before chemotherapy, radiation, or surgery.

If you're making use of the liquid type of this medication, use a measuring that is special or device to measure out your prescribed dose. Do not use a household spoon because you may not get the dose that is correct.

Take any other doses as directed by your physician. Ondansetron might be taken on to three times a for 1 to 2 days after your chemotherapy or radiation treatment is finished day. If you are taking this medication on a prescribed schedule, take it regularly in order to get the most benefit from it. Each day to help you remember, take it at the same times.

Dosage is situated on your medical condition and response to therapy. The dosage for children may also be based on age and weight. The usual dose that is maximum patients with severe liver problems is 8 milligrams in 24 hours. Take this medication exactly as directed. Do not take more medication or take it more often than prescribed. Pose a question to your pharmacist or doctor in the event that you have questions.

Inform your doctor if your condition does maybe not improve or if it worsens.

adverse Results

Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your physician quickly.

Understand that your doctor has recommended this medicine because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have side that is serious.

Tell your doctor right away if any of those not likely but serious negative effects happen: stomach pain, muscle tissue spasm/stiffness, eyesight modifications (age.g., temporary lack of eyesight, blurred vision).

Get medical help right away if some of these unusual but very serious side effects occur: chest pain, slow/fast/irregular heartbeat, serious dizziness, fainting.

This medication may increase serotonin and seldom cause a very condition that is serious serotonin syndrome/toxicity. The risk increases you take (see Drug Interactions section) if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, lack of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

a really severe allergic reaction to this drug is unlikely, but stop taking this medication and seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially of the face/tongue/throat), serious dizziness, trouble breathing.

This is not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the usa -

Call your doctor for medical advice about side-effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about part impacts. You may report adverse effects to Health Canada at 1-866-234-2345.


Before taking ondansetron, tell your medical professional or pharmacist if you are allergic to it; or to other serotonin blockers (e.g., granisetron); or if you have any other allergies. This product may contain ingredients that are inactive that may cause allergic responses or other problems. Keep in touch with your pharmacist for more information.

Before using this medicine, tell your doctor or pharmacist your medical history, especially of: irregular heartbeat, liver disease, stomach/intestinal problems (age.g., present abdominal surgery, ileus, swelling).

Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can hardly ever cause severe (rarely deadly) fast/irregular heartbeat and other signs (such as for example severe dizziness, fainting) that require medical attention immediately.

The danger of QT prolongation may be increased if you have certain medical conditions or are using other drugs that could cause QT prolongation. Before using ondansetron, tell your physician or pharmacist of all of the drugs you are taking and if you have any of the following conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation within the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the bloodstream may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Speak to your doctor about using ondansetron properly.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To minimize dizziness and lightheadedness, get up slowly whenever rising from a sitting or lying position.

Older adults may be more sensitive to the medial side aftereffects of this drug, especially QT prolongation (see above).

This medication should be used only if clearly required during maternity. Discuss the risks and benefits along with your doctor.

It isn't understood whether this drug passes into breast milk. Consult your doctor before breast-feeding.

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