This medication can be used to avoid or treat gout assaults (flares). Usually gout symptoms develop suddenly and involve only one or a joints that are few. The big toe, leg, or ankle joints are most often affected. Gout is caused by too much acid that is uric the blood. When uric acid levels into the blood are way too high, the uric acid may form hard crystals in your joints. Colchicine functions by decreasing swelling and lessening the create up of the crystals crystals that hurt into the affected joint(s).
This medication is also utilized to avoid assaults of pain in the abdomen, upper body, or joints caused by a specific inherited disease (familial Mediterranean fever). It is thought working by decreasing your production of a certain protein (amyloid A) that builds up in people with familial Mediterranean fever.
Colchicine is not a pain medication and may perhaps not be used to alleviate other factors behind discomfort.
DIFFERENT USES: This section contains uses of this drug that are not detailed in the approved labeling that is professional the drug but that could be recommended by your health care professional. Use this medication for a condition that is listed in this part only if it is therefore prescribed by your health care professional.
This medication may be used to also reduce swelling and inflammation associated with sac that covers the outside of the heart, an ailment called pericarditis.
Read the Medication Guide provided by your pharmacist you get a refill before you start taking colchicine and each time. If you have any relevant concerns about the information, ask your doctor or pharmacist.
Take this medication by mouth with or without meals, precisely as directed by your medical professional. Dosing recommendations vary widely and may vary from the recommendations that are following. Taking more than the recommended dose might maybe not increase this medication's effectiveness and may increase your risk for side-effects. Ask your doctor or pharmacist for lots more details.
If you are taking this medication to treat a gout attack, follow the directions carefully given by your doctor. This medication works best at the first sign of an attack if you take it. The suggested dose is 1.2 milligrams at the sign that is first of attack, followed by 0.6 milligrams one hour later. The maximum recommended dose is 1.8 milligrams taken over a period that is 1-hour. Ask your physician in advance about how soon you can repeat treatment using this medication if another gout is had by you attack.
If you are taking this medication to prevent gout attacks or for pericarditis, ask your doctor about the dose and schedule you should follow. Carefully follow your doctor's directions.
The usual dose is 1.2 to 2.4 milligrams daily if you are taking this medication to prevent attacks of pain caused by familial Mediterranean fever. The dose that is total be taken once daily or divided into two doses a day. Your physician may have to adjust your dose to control your symptoms or if you have adverse effects.
The dosage is based on your medical condition, other drugs/foods you may be taking, and response to treatment. To reduce your risk for serious adverse effects, do not increase your dose, frequently take it more, and take it for a bit longer than directed by your medical practitioner. Severe unwanted effects may take place even at typical prescribed doses.
Should your physician directs one to take colchicine regularly, use it frequently to obtain the benefit that is most from it. To help you remember, take it at the same time(s) each day.
Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.
If it worsens if you are taking this medication to treat symptoms due to familial Mediterranean fever, tell your doctor if your condition does not improve or.
Diarrhoea, nausea, cramping, abdominal pain, and vomiting may occur. If any of these effects persist or aggravate, tell your doctor or pharmacist promptly.
Keep in mind that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious side effects.
Stop using this medication and get medical help right away if some of these very severe side-effects happen: unusual bleeding/bruising, serious diarrhoea or vomiting, muscle weakness or pain, numbness/tingling in your fingers or toes, pale or gray color of this lips/tongue/palms of fingers, signs of infection (such as for instance temperature, persistent sore throat), unusual weakness/tiredness, fast heartbeat, shortness of breath, change in the total amount of urine.
A really serious reaction that is allergic this drug is rare. However, seek immediate medical attention if you see any symptoms of a critical allergic attack, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In america -
Phone your doctor for medical advice about side-effects. You might report effects that are side FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about adverse impacts. You may possibly report effects that are side Health Canada at 1-866-234-2345.
Before taking this medicine, inform your medical professional or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Speak to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver issues (such as cirrhosis).
Alcohol can decrease this drug's effectiveness. Limit liquor while taking this drug.
This medication can affect how well your body absorbs some foods and nutritional elements (such as vitamin B12). Check with your doctor or pharmacist for more details.
Before having surgery, tell your doctor or dental practitioner about all the products you employ (including prescription drugs, nonprescription drugs, and herbal services and products).
Older adults may be more sensitive to the relative side effects of this medication, especially muscle mass weakness/pain and numbness/tingling in their fingers or toes.
Colchicine can decrease sperm production, which might impact the capability of a male to father a kid. Check with your physician for more information.
During maternity, this medication should be properly used only when clearly needed. Discuss the risks and benefits along with your doctor.
This medicine passes into breast milk. While there has been no reports of harm to nursing babies, consult your physician before breast-feeding. Your doctor may suggest that you separate the time(s) you take your medication apart from breast-feeding.
Airmail: 2-3 business weeks, EMS: 3-8 business days.
Airmail: 2-3 business weeks, EMS: 3-8 business days.