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Precautions

 Do NOT use Colchicine if:

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• the patient is often a child with gout

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• you've liver or kidney problems and you're simply also taking certain other medicines (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir or any medicine made up of ritonavir, saquinavir, telithromycin)

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Contact your medical professional or health care provider straight away if all of these connect with you.

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Some medical ailments may talk with Colchicine . Tell your doctor or pharmacist if you have any health conditions, in particular when any from the following apply to you:

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• if you happen to be pregnant, likely to get pregnant, or are breast-feeding

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• if you might be taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• for those who have allergies to medicines, foods, or any other substances

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• for those who have a blood disorder, stomach or bowel irregularity, heart problems, or liver or kidney problems, or if you happen to be having dialysis

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Some medicines may communicate with Colchicine . Tell your health care provider if you're taking another medicines, especially any of the following:

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• Digoxin, fibrates (eg, fenofibric acid), gemfibrozil, or HMG-Co A reductase inhibitors (eg, simvastatin) for the reason that likelihood of severe or fatal muscle problems may be increased

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• Aprepitant, atazanavir, clarithromycin, cyclosporine, diltiazem, erythromycin, fluconazole, HIV protease inhibitors (eg, fosamprenavir), indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ranolazine, ritonavir or any medicine made up of ritonavir, saquinavir, telithromycin, or verapamil because they could raise the likelihood of Colchicine 's unwanted effects, including severe or fatal unwanted effects

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• Sympathomimetics (eg, pseudoephedrine, albuterol) for the reason that probability of their unwanted side effects could possibly be increased

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This will not be a whole list of all interactions that will occur. Ask your doctor if Colchicine may interact with other medicines which you take. Check with your doctor prior to starting, stop, or change the dose from a medicine.

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Important safety information

• Do NOT take greater than the recommended dose without checking with your physician.

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• Check with your physician when you use medicines that could potentially cause drowsiness (eg, sleep aids, muscle relaxers) if you are using Colchicine ; it might improve their effects. Ask your friendly phamacist if you have questions regarding which medicines may cause drowsiness.

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• Colchicine may lower the ability of your body to fight infection. Avoid exposure to folks who suffer from colds or infections. Tell your doctor possibly warning signs of infection like fever, sore throat, rash, or chills.

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• Colchicine may lessen the variety of clot-forming cells (platelets) inside your blood. Avoid activities that could cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor in case you have dark, tarry, or bloody stools.

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• Accidental ingestion or overdose of Colchicine continues to be fatal in youngsters and adults. Keep Colchicine out of the reach of kids. In case of an overdose, call a doctor or poison control center straight away.

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• If nausea, vomiting, or diarrhea occurs, ask your physician for methods to lessen these effects. Contact a medical expert without delay in case you experience severe or persistent diarrhea, nausea, or vomiting.

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• Tell a medical expert or dentist which you take Colchicine prior to deciding to get any medical or dental treatments, emergency care, or surgery.

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• Rarely, Colchicine may decrease fertility that face men. Discuss any queries or concerns with your physician.

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• Colchicine may obstruct certain diagnostic tests, including urine tests for red blood cells or hemoglobin. Be sure your doctor and lab personnel know you are taking Colchicine .

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• Lab tests, including complete blood cell counts, kidney function, and liver function, might be performed whilst you use Colchicine . These tests could possibly be used to monitor your trouble or look for side effects. Be sure to keep all doctor and lab appointments.

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• Use Colchicine with caution in the elderly; they might be more understanding of its effects, including muscle and nerve problems.

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• Colchicine must be used with warning in kids younger 4 years; safety and effectiveness in these children weren't confirmed.

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• Pregnancy and breast-feeding: If you become pregnant, contact your medical professional. You will need to discuss the rewards and perils associated with using Colchicine if you are pregnant. Colchicine is located in breast milk. If you're or will be breast-feeding while you use Colchicine , consult your doctor. Discuss any possible risks for a baby.

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