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Precautions

Do NOT use Effexor XR if:

• you're allergic to any ingredient in Effexor XR
• you are taking or took a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the past 14 days
• you take a fenfluramine derivative (eg, dexfenfluramine), methylene blue, nefazodone, sibutramine, or tryptophan.

Contact a medical expert or physician right away if some of these sign up for you.

Some medical ailments may connect to Effexor XR. Tell your medical professional or pharmacist when you have any medical ailments, especially if any with the following sign up for you:

• if you're pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines, foods, or another substances
• if you or even a loved one features a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
• if you have a history of seizures, cardiovascular disease (eg, heart failure, irregular heartbeat), abnormal electrocardiograms (ECGs), a newly released cardiac arrest, hypertension, an overactive thyroid, liver problems, lung problems, kidney problems, stomach or bowel bleeding, blood or bleeding problems, increased eye pressure (eg, glaucoma), neurological system problems, or metabolism problems
• if you are dehydrated, have low blood sodium levels, or drink alcohol
• if you will end up having electroconvulsive therapy (ECT).

Some medicines may connect to Effexor XR. Tell your medical provider if you consider any other medicines, especially any of the following:

• Certain diet medicines (eg, phentermine, fenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), methylene blue, metoclopramide, nefazodone, rasagiline, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, duloxetine),St. John's wort, tramadol, trazodone, tricyclic antidepressants (eg, amitriptyline), or tryptophan because severe unwanted side effects, say for example a reaction which could include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur
• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) as the chance of bleeding, including stomach bleeding, could be increased
• Diuretics (eg, furosemide, hydrochlorothiazide) as the chance of low blood sodium levels might be increased
• Azole antifungals (eg, ketoconazole) or cimetidine given that they may increase the chance of Effexor XR's unwanted effects
• Cyproheptadine as it may decrease Effexor XR's effectiveness
• Aripiprazole, haloperidol, phenothiazines (eg, chlorpromazine, thioridazine), or risperidone because the likelihood of their side effects could be increased by Effexor XR.

This will not be a whole list of all interactions which could occur. Ask your doctor if Effexor XR may connect to other medicines which you take. Check together with your health care provider before starting, stop, or alter the dose from a medicine.

Important safety information:

• Effexor XR may cause drowsiness, dizziness, or blurred vision. These effects could possibly be worse if you take it with alcohol or certain medicines. Use Effexor XR with caution. Do not drive or perform other possible unsafe tasks unless you recognize how you react to it.
• Do not are drinking alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you happen to be using Effexor XR without checking along with your doctor; it could enhance their effects. Ask your friendly phamacist when you have questions on which medicines might cause drowsiness.
• Several weeks may pass before your symptoms improve. Do NOT take greater than the recommended dose, or use for over prescribed without checking along with your doctor.
• Children, teenagers, and the younger generation who take Effexor XR may be at increased risk for suicidal thoughts or actions. Watch all patients who take Effexor XR closely. Contact a doctor simultaneously if new, worsened, or sudden symptoms for example depressed mood; anxious, restless, or irritable behavior; panic and anxiety attacks; or any unusual difference in mood or behavior occur. Contact your physician without delay if any indications of suicidal thoughts or actions occur.
• Serotonin syndrome can be a possibly fatal syndrome that could be due to Effexor XR. Your risk could be greater for Effexor XR with certain other medicines (eg, "triptans," MAOIs, SSRIs). Symptoms can include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact a medical expert immediately when you have all of these symptoms.
• Neuroleptic malignant syndrome (NMS) is often a possibly fatal syndrome that may be caused by Effexor XR. Symptoms might include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact a medical expert at once for those who have all of these symptoms.
• If a medical expert informs you to prevent taking Effexor XR, you will have to wait for period of time before you begin to adopt certain other medicines (eg, MAOIs, nefazodone, thioridazine). Ask a medical expert when you ought to start to consider your new medicines after you've stopped taking Effexor XR.
• Effexor XR may rarely spark a prolonged, painful erection. This could happen even when you happen to be not having sexual intercourse. If this is not treated straight away, it could possibly lead to permanent sexual dysfunctions for example impotence. Contact your medical professional straight away in such a circumstance.
• Lab tests, including blood pressure and blood levels of cholesterol, might be performed whilst you use Effexor XR. These tests might be used to monitor your condition or look for unwanted effects. Be sure to keep all doctor and lab appointments.
• Use Effexor XR with caution inside the elderly; they may be more sensitive to its effects, especially low blood sodium levels.
• Caution is advised when utilizing Effexor XR in youngsters; they could possibly be more responsive to its effects, especially increased likelihood of suicidal thoughts or actions.
• Effexor XR needs to be used with extreme care in youngsters; safety and effectiveness in kids weren't confirmed.
• Effexor XR could potentially cause weight changes and growth changes. Children and teenagers may require regular weight and growth checks while they take Effexor XR.

Pregnancy and breast-feeding: Effexor XR could potentially cause trouble for the fetus if it is used over the past a few months of pregnancy. If you become pregnant, speak to your doctor. You will need to discuss the advantages and risks of using Effexor XR while you happen to be pregnant. Effexor XR is located in breast milk. Do not breastfeed while taking Effexor XR.