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Tofranil (Imipramine) is a small grouping of drugs called tricyclic antidepressants. Imipramine affects chemicals in the brain that may become unbalanced.
It is employed to help remedy the signs of depression.
This medicine doubles for purposes other than those placed in medicines guide.


Take this medication the same manner it had been prescribed for you personally. Do not take the medication in larger amounts, or take it for over recommended because of your doctor. Your doctor may occasionally alter your dose to successfully get the best comes from prescription drugs. Follow the directions on your prescription label.
If you need to have almost any surgery, tell the surgeon beforehand you are taking imipramine. You may need to stop while using medicine for any small amount of time.
Do not stop using imipramine without first actually talking to your doctor. You may need to use less when you stop the medication completely. Stopping medicines suddenly may cause that you have unpleasant unwanted side effects. It may take as much as 21 days of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with a medical expert if your symptoms do not improve after 30 days of treatment.

If you missed the dose go when you remember. If it's almost time for your next dose, skip the missed dose and go ahead and take medicine at the next regularly scheduled time. Do not take extra medicine to make the missed dose.

Seek emergency medical help if you think you might have used an excessive amount this medicine. An overdose of imipramine might be fatal.
Symptoms of your imipramine overdose can sometimes include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, sweating, muscle stiffness, swelling, breathlessness, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma.


Take this medicine as prescribed because of your doctor.


Store imipramine at room temperature away from moisture as well as heat.


Active Ingredient: Imipramine

Tofranil can be a tricyclic antidepressant. It works by improving the activity of certain chemicals within the brain that assist elevate mood.

Side Effects

Get emergency medical help if you've these signs of the allergic reaction: hives; breathlessness; swelling of your respective face, lips, tongue, or throat.

Call your doctor immediately if you might have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, sleep problems, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor immediately if you have all of these serious unwanted effects:

fast, pounding, or uneven pulse rate;

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness or weakness, especially on one side from the body;

sudden headache, confusion, problems with vision, speech, or balance;

feeling lacking breath, in spite of mild exertion;

swelling, rapid extra weight;

confusion, hallucinations, or seizure (convulsions);

easy bruising or bleeding, unusual weakness;

restless muscle movements with your eyes, tongue, jaw, or neck;

urinating pretty much than usual;

extreme thirst with headache, nausea, vomiting, and weakness;

skin rash, bruising, severe tingling, numbness, pain, or muscle weakness.

Less serious unwanted side effects could possibly be very likely to occur, for example:

nausea, vomiting, stomach pain, loss in appetite;

constipation or diarrhea;

dry mouth, unpleasant taste;

weight changes;

weakness, lack of coordination;

feeling dizzy, drowsy, or tired;


blurred vision, headache, ringing in your ears;

breast swelling (in men or women); or

decreased sexual libido, impotence, or difficulty using an orgasm.

Tofranil is usually to be used only by the patient for whom it's prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, consult your physician.


Do not use Tofranil if:

you're allergic to the ingredient in Tofranil;

you might have taken furazolidone or even a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) within the last fourteen days, or if you adopt astemizole, droperidol, or terfenadine.

you might be dealing with a current heart attack.
Contact your physician or health care provider straight away if some of these apply to you.

Some medical ailments may talk with Tofranil . Tell your doctor or pharmacist if you have any medical ailments, especially if any of the following apply to you:

if you happen to be pregnant, likely to get pregnant, or are breast-feeding

if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you might have allergies to medicines, foods, or another substances

if you drink alcohol-containing beverages daily or you might have a history of alcohol abuse

if you take thyroid medicine or you might have a reputation overactive thyroid, glaucoma, heart problems, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating

if you might have a reputation suicidal thoughts or behavior, bipolar disorder, or another mental disorders; you might be undergoing electroshock therapy; or you're scheduled to own any surgery.

Some MEDICINES MAY INTERACT with Tofranil . Tell your physician if you adopt another medicines, especially any in the following:

Azole antifungals (eg, fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (eg, chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or terbinafine since they could raise the risk of Tofranil 's side effects

Arsenic, astemizole, droperidol, furazolidone, MAOIs (eg, phenelzine), pimozide, streptogramins (eg, dalfopristin), terfenadine, or tramadol as the risk of high blood pressure, serious heart related illnesses (eg, irregular heartbeat), or seizures could be increased

Barbiturates (eg, phenobarbital) or phenytoin simply because they may decrease Tofranil 's effectiveness

Anticholinergics (eg, benztropine), carbamazepine, or sympathomimetics (eg, phenylephrine) since the likelihood of their unwanted side effects could be increased by Tofranil

Clonidine, guanethidine, or guanfacine as their effectiveness could be decreased by Tofranil

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