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Micronase (Glyburide) is definitely an oral diabetes medicine that can help control glucose levels.

Glyburide is employed to treat diabetes type 2 symptoms.

This drugs are not for treating type 1 diabetes.

Glyburide may also be used for other purposes not listed on this medication guide.


Take just as prescribed through your doctor. Do not take in larger or smaller amounts or longer than recommended. Follow the directions on the prescription label. Your doctor may occasionally make positive changes to dose to ensure that you receive the best results.

Take glyburide together with your first meal for the day, unless your doctor lets you know otherwise.

Your blood sugar will need to be checked often, and you will need other blood tests at your physician's office. Visit your medical professional regularly.
Know the indications of low blood sugar levels (hypoglycemia) and the way to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a method to obtain sugar obtainable in case you've got signs of low blood sugar levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you've got severe hypoglycemia and should not eat or drink, readily injection of glucagon. Your doctor can give you a prescription for any glucagon emergency injection kit and show you how to give the injection.

Also watch out for indications of blood sugar levels that is excessive (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and weight reduction.

Check your blood glucose carefully throughout a time of stress or illness, should you travel, exercise more than usual, consume alcohol, or skip meals. These things can affect your glucose levels as well as your dose needs may also change.

Your doctor might prefer that you stop taking glyburide for a limited time in the event you get sick, have a very fever or infection, or if you have surgical treatment or a medical emergency.
Ask a medical expert how you can adjust your glyburide dose if required. Do not alter your medication dose or schedule without your medical professional's advice.

If you'll find any adjustments to the manufacturer, strength, or kind of glyburide you have, your dosage needs may change. Always check your refills to successfully have received the right logo and kind of medicine prescribed by your doctor.


Take as prescribed by your doctor.


Store at room temperature, shielded from moisture, heat, and light.


Active ingredient: Glyburide

Side Effects

Stop using glyburide and obtain emergency medical help if you've any of these signs of a hypersensitive reaction: hives; breathlessness; swelling of one's face, lips, tongue, or throat. Stop taking medicines and call your medical professional immediately if you've these serious negative effects:

nausea, stomach pain, low fever, loss in appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots beneath your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious unwanted effects may include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete set of unwanted effects while others may occur. Call your doctor for medical health advice about negative effects.


You must avoid using medicines in case you are allergic to glyburide, or:

in case you are receiving treatment with bosentan (Tracleer);

if you've got type 1 diabetes; or

in case you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

To be sure to can safely take glyburide, tell your medical professional if you've got all of these other concerns:

hemolytic anemia (too little red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

in case you are allergic to sulfa drugs; or

if you've been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may increase your chance of serious heart disease. However, not treating your diabetes may damage your heart and also other organs. Talk to your medical professional in regards to the risks and benefits of your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication nearby the time of delivery. Tell your physician if you are pregnant or prefer to get pregnant while using the this medication. It is not known whether glyburide passes into breast milk or if it may harm a nursing baby.

Do not use prescription drugs without telling your doctor in case you are breast-feeding your baby. Older adults could be more prone to have low blood glucose while taking glyburide.


Important safety information:

You should not use medicines in case you are allergic to glyburide, if you are being treated with bosentan (Tracleer), if you have type 1 diabetes, or in the event you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

Before taking glyburide, tell your medical professional should you are allergic to sulfa drugs, if you might have been using insulin or chlorpropamide (Diabinese), or if you might have hemolytic anemia (an absence of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care not to let your blood glucose get too low. Low blood sugar levels (hypoglycemia) can take place in case you skip a meal, exercise to much time, consume alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets together with you in case you might have low blood glucose levels. Other sugar sources include orange juice and milk. Be sure your family and pals know the best way to help you in an emergency.

Drug interactions

Tell your physician about all other medications you have, especially:

a blood thinner including warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor such as enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), among others; or

an antibiotic like ciprofloxacin (Cipro), levofloxacin (Levaquin), while others.

Using certain medicines causes it to be more difficult for you to definitely tell when you've low blood glucose levels. Tell your physician in the event you use these things:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers including atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.

You might be more prone to have hyperglycemia (high blood glucose levels) if you take glyburide with:


diuretics (water pills);

steroids (prednisone and others);

phenothiazines (Compazine yet others);

thyroid medicine (Synthroid among others);

birth control pills along with other hormones;

heart or blood pressure level medications (Cartia, Cardizem, Nifedical, Covera, Verelan, among others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

seizure medicines (Dilantin while others); and

diet pills or medicines to treat asthma, colds or allergies.

You may be prone to have hypoglycemia (low blood sugar levels) should you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, while others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or any other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, while others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists usually are not complete and you can find many other medicines that may increase or decrease the effects of glyburide on reducing your blood glucose. Tell your medical professional about all medications you utilize. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your physician.


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