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Eldepryl is indicated just as one adjunct within the management of Parkinsonian patients being treated with levodopa/carbidopa who exhibit deterioration in the quality of the response to this therapy.


Take this medicine only as directed by your doctor. Do not take a greater portion of it, do not take on it more frequently, and do not take on it for a longer time than a medical expert ordered.

It is better to consider this medicine before breakfast and without liquids.

If you happen to be with all the disintegrating tablet, make certain your hands are dry prior to deciding to handle named. Do not open the blister pack which has today until you are ready to go. Remove named in the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet over the foil. Do not break or split the tablet. Place named for the top of your tongue, where it will melt quickly. Do not eat food or drink liquids for 5 minutes before or after using this medicine.

If you miss a dose on this medicine, get it at the earliest opportunity. However, whether it is almost time for your forthcoming dose, skip the missed dose and go back to your family dosing schedule. Do not double doses.


The dose of this medicine changes for several patients. Follow a medical expert's orders or directions for the label. The following information includes merely the average doses of this medicine. If your dose is different, don't put it back unless your physician informs you to do so.

The quantity of medicine that you just take depends for the strength in the medicine. Also, the quantity of doses you adopt on a daily basis, enough time allowed between doses, and also the length of time you take the medicine depend for the disease for which you might be while using the medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine in the closed container at room temperature, faraway from heat, moisture, and direct light. Keep from freezing.
Keep out of your reach of youngsters.
Do not keep outdated medicine or medicine will no longer needed.


Eldepryl can be a levorotatory acetylenic derivative of phenethylamine. It is commonly described within the clinical and pharmacological literature as l-deprenyl.

Side Effects

Along using its needed effects, medicine could potentially cause some uncomfortable side effects. Although not these side effects may occur, whenever they occur they might need medical assistance.

Check with a medical expert immediately if any of the following unwanted side effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements in the body
increased sensitivity of the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly if arising coming from a lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling issues that are not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches within the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling within the hands, feet, or lips
puffing from the cheeks
rapid or worm-like movements from the tongue
restlessness or wish to keep moving
severe stomach pain
shakiness within the legs, arms, hands, or feet
shortness of breath
swelling in the feet or lower legs
swelling or inflammation in the mouth
tightness inside the chest
trembling or shaking with the hands or feet
twisting movements with the body
uncontrolled chewing movements
uncontrolled movements from the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that appears like coffee grounds

Get emergency help immediately if the following symptoms of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure level
severe spasm in which the head and heels are bent backward along with the body arched forward
troubled breathing

Some negative effects may occur very often usually do not need medical assistance. These side effects might have to go away during treatment since your body adjusts on the medicine. Also, your overall health care professional could possibly inform you of ways to prevent or reduce many of these unwanted effects. Check along with your health care professional if the following side effects continue or are bothersome or if you've any queries about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning with the lips, mouth, or throat
dryness or soreness in the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing inside ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing in the eyelids
unusual a feeling of well-being
unusual weight loss
voice changes

Other unwanted side effects unpublished could also appear in some patients. If you notice every other effects, check along with your healthcare professional.


It is critical that your physician check your progress at regular visits to allow for modifications in your dose and to look for any negative effects.

Do not take selegiline if you've used meperidine (e.g., Demerol®) or even an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 2 weeks. If you do, you may develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body's temperature, higher than normal blood pressure, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you're employing this medicine. Using these medicines together might cause negative effects.

Selegiline could cause serious side effects when used in addition to some antidepressants. Tell a medical expert if you might have used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past two weeks.

When selegiline is taken at doses of 10 mg or less each day to the treatments for Parkinson's disease, there won't be any restrictions on food or beverages you eat or drink. However, the opportunity exists that dangerous reactions, like sudden high blood pressure level, may occur if doses higher than those useful for Parkinson's disease are taken with foods, beverages, or another medicines. These foods, beverages, and medicines include:

Also, for about two weeks after you stop taking this medicine, these foods, beverages, as well as other medicines may continue to react with selegiline whether or not this was drawn in doses greater than those usually used by Parkinson's disease.

Check with your medical professional or hospital er immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you might be using this medicine. These may be signs and symptoms of a serious side effect which will have a very doctor's attention.

Dizziness, lightheadedness, or fainting may occur, particularly when you will get up coming from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, consult your doctor.

Selegiline may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt items of ice within your mouth, or utilize a saliva substitute. However, should your mouth will continue to feel dry in excess of fourteen days, check together with your health practitioner or dentist. Continuing dryness of the mouth may increase the opportunity of dental disease, including dental cairies, gum disease, and fungus infections.

It is very important that your physician look at your skin for melanoma (tumor) regularly if you've got Parkinson's disease.

Do not stop taking this medicine without first checking with your doctor. Your doctor may want that you reduce gradually the amount you are taking before stopping completely.

Hallucinations may occur in some patients. This is more widespread with elderly patients. If you have hallucinations, seek advice from your physician.

Some individuals who have used this medicine had unusual alterations in their behavior. Talk with your medical professional in case you start experiencing difficulity with gambling or increased sexual libido while employing this medicine.

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