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Eldepryl is indicated just as one adjunct inside treatments for Parkinsonian patients receiving care with levodopa/carbidopa who exhibit deterioration within the quality of the reaction to this therapy.


Take this medicine only as directed by your doctor. Do not take much more of it, don't take it often, and do not take on it a bit longer than your medical professional ordered.

It is best to take this medicine before breakfast and without liquids.

If you are using the disintegrating tablet, make certain the hands are dry before you decide to handle these days. Do not open the blister pack that contains today until you are ready to get it. Remove the tablet from your blister pack by peeling back the foil, then taking the tablet out. Do not push named with the foil. Do not break or split today. Place these days about the top of your tongue, where it will melt quickly. Do not eat food or drink liquids for 5 minutes before or after using this medicine.

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If you miss a dose on this medicine, get it at the earliest opportunity. However, if it is almost time for your next dose, skip the missed dose and get back on your family dosing schedule. Do not double doses.


The dose on this medicine will change for various patients. Follow your doctor's orders or even the directions around the label. The following information includes exactly the average doses on this medicine. If your dose is unique, usually do not change it unless a medical expert notifys you to take action.

The volume of medicine that you just take depends about the strength of the medicine. Also, the quantity of doses you take on a daily basis, some time allowed between doses, and also the amount of time you take the medicine depend around the problem for which you're while using medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine in a closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.
Keep out from the reach of children.
Do not keep outdated medicine or medicine will no longer needed.

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Eldepryl can be a levorotatory acetylenic derivative of phenethylamine. It is commonly known inside the clinical and pharmacological literature as l-deprenyl.

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Side Effects

Along featuring its needed effects, a medicine could potentially cause some uncomfortable side effects. Although not many of these unwanted effects may occur, should they happen they may need medical assistance.

Check with a medical expert immediately if these things unwanted effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements with the body
increased sensitivity with the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or other mental changes
nausea and vomiting (severe)
stiff or sore neck

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Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly when waking up from the lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling stuff that usually are not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches inside the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling inside hands, feet, or lips
puffing in the cheeks
rapid or worm-like movements from the tongue
restlessness or desire to keep moving
severe stomach pain
shakiness inside legs, arms, hands, or feet
shortness of breath
swelling from the feet or lower legs
swelling or inflammation of the mouth
tightness in the chest
trembling or shaking of the hands or feet
twisting movements from the body
uncontrolled chewing movements
uncontrolled movements of the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material seems like coffee grounds

Get emergency help immediately if the following symptoms of overdose occur:

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Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure levels
severe spasm in which the head and heels are bent backward and the body arched forward
troubled breathing

Some unwanted side effects may occur very often don't need medical attention. These negative effects might go away during treatment because your body adjusts on the medicine. Also, your quality of life care professional could possibly inform you of approaches to prevent or reduce some side effects. Check using your health care professional if any of the following side effects continue or are bothersome or if you have questions about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

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Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning from the lips, mouth, or throat
dryness or soreness of the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing inside the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing of the eyelids
unusual a sense well-being
unusual weight loss
voice changes

Other unwanted side effects unlisted might also happen in some patients. If you notice some other effects, check with your medical practioner.

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It is essential that a medical expert look at progress at regular visits to allow for modifications in your dose also to look for any negative effects.

Do not take selegiline if you've got used meperidine (e.g., Demerol®) or an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 2 weeks. If you do, you might develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body's temperature, very high blood pressure levels, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you're using this medicine. Using these medicines together can cause unwanted side effects.

Selegiline could potentially cause serious negative effects when used together with some antidepressants. Tell your medical professional if you might have used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past 14 days.

When selegiline is taken at doses of 10 mg or less per day for your management of Parkinson's disease, there aren't any restrictions on food or beverages you take in or drink. However, the chance exists that dangerous reactions, like sudden high blood pressure, may occur if doses greater than those used for Parkinson's disease are taken with particular foods, beverages, or another medicines. These foods, beverages, and medicines include:

Also, for around 2 weeks once you stop using this medicine, due to the fact, beverages, and also other medicines may continue to react with selegiline if it was taken in doses above those usually useful for Parkinson's disease.

Check with your doctor or hospital emergency room immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you might be taking this medicine. These may be signs of a serious complication that will have a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, especially when you will get up from your lying or sitting position. Getting up slowly could help. If the problem continues or gets worse, check with your physician.

Selegiline could potentially cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice with your mouth, or use a saliva substitute. However, should your mouth is constantly on the feel dry in excess of two weeks, check using your health practitioner or dentist. Continuing dryness with the mouth may increase the chance of dental disease, including cavities, gum disease, and fungus infections.

It is important that your doctor look at your skin for melanoma (tumor) regularly if you've Parkinson's disease.

Do not stop investing in this medicine without first checking with your doctor. Your doctor might prefer you to reduce gradually the amount you happen to be taking before stopping completely.

Hallucinations may occur in some patients. This is more widespread with elderly patients. If you might have hallucinations, consult your physician.

Some folks who suffer from used this medicine had unusual changes in their behavior. Talk with a medical expert in the event you start experiencing difficulity with gambling or increased sex drive while applying this medicine.

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