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Mestinon (Pyridostigmine) affects chemicals within the body that are mixed up in communication between nerve impulses and muscle movement.

Pyridostigmine is employed to take care of the the signs of myasthenia gravis. It is also employed in military personnel who had been exposed to nerve gas.

Pyridostigmine doubles for purposes unpublished in this medication guide.


Take exactly as prescribed through your doctor. Do not take in larger or smaller amounts and over recommended. Follow the directions on your prescription label.
Take this medicine with food or milk when it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill might cause excessive drug to be removed at once.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not having a regular table spoon. If you do not use a dose measuring device, ask your pharmacist first.

The amount and timing of the drugs are very important for the success of one's treatment. Carefully follow your medical professional's instructions about how precisely much medicine to look at and when to look at it.

Your doctor may occasionally make positive changes to dose to ensure that you obtain the best results. You may be asked to keep a daily record of once you took each dose and the way long the consequences lasted. This will help a medical expert determine if your dose should be adjusted.
If you need surgery, tell the surgeon before hand that you're using pyridostigmine. You may need to stop with all the medicine for a small amount of time. Store at room temperature from moisture and warmth.


Take the medicine as prescribed from your doctor.


Keep the tablets in their original container, along with the canister of moisture-absorbing preservative that comes with this medicine.


Active ingredient: Pyridostigmine

Side Effects

Get emergency medical help if you have some of these signs and symptoms of a hypersensitive reaction: hives; difficulty breathing; swelling of the face, lips, tongue, or throat. Stop using pyridostigmine and call your doctor at the same time when you have these serious side effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, anxiety attacks;

seizure (convulsions); or

worsening or no improvement in your signs of myasthenia gravis.

Less serious unwanted effects may include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This is just not a complete list of side effects among others may occur. Call your medical professional for medical advice about side effects.


You should not use pyridostigmine if you are allergic to it, or if you possess a bladder or bowel obstruction.

To be sure you can safely take pyridostigmine, tell your doctor when you have any of these other difficulties:


kidney disease;

an ulcer or other serious stomach disorder;

high hypertension, cardiovascular disease;

overactive thyroid; or

a good reputation for seizures.

It is not known whether pyridostigmine will harm an baby. Tell your medical professional if you are pregnant or intend to conceive with all the medicines. It just isn't known whether pyridostigmine passes into breast milk or if it could harm a nursing baby. Do not use medicines without telling your medical professional in case you are breast-feeding a baby.

Drugs interaction 

Tell your doctor about other medicines you have, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, among others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications for example darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators like ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that have an antihistamine such as diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication for example quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), while others;

irritable bowel medications like dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to take care of Alzheimer's dementia, such as donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid like betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list isn't complete along with other drugs may interact with pyridostigmine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your doctor.

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