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Promethazine is in a small grouping of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing what of chemicals in your brain. Promethazine also acts just as one antihistamine. It blocks the consequences in the naturally sourced chemical histamine inside your body.

Promethazine is used to take care of hypersensitivity for example itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as being a sedative or sleep aid.

Promethazine is just not for usage for treating signs of asthma, pneumonia, or other lower respiratory tract infections.

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Take promethazine just as prescribed from your doctor. Do not take it in larger amounts or for over recommended. Follow the directions on your own prescription label.

Your doctor may occasionally change your dose to ensure that you get the best comes from this medication.

Promethazine can be taken with or without food or milk.

Measure liquid medicine with a marked measuring spoon or medicine cup, not which has a regular table spoon. If you usually do not use a dose-measuring device, ask your pharmacist for just one.

Call your doctor if your symptoms tend not to improve, or if they worsen while taking promethazine.

This medication could cause one to have unusual results with certain lab tests. Tell any doctor who treats you that you're using promethazine.

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Seek emergency medical attention if you feel you've used an excessive amount of this medicine. Overdose symptoms might include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


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Take becoming prescribed because of your doctor.

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Store promethazine at room temperature faraway from moisture, heat, and light.


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Side Effects

Get emergency medical help if you have these signs of a hypersensitivity: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using promethazine and call a medical expert simultaneously if you have these serious side effects:

twitching, or uncontrollable movements of your respective eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulties with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling like you might faint;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing in the skin or eyes);

urinating lower than usual you aren't in any respect;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy pores and skin; or

slow heartrate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine unwanted side effects may include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing inside your ears;

weight gain, swelling inside your hands or feet;

impotence, trouble through an orgasm; or


This just isn't a complete set of unwanted effects and others may occur. Tell your physician about any unusual or bothersome complication.

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Stop using promethazine and call your physician immediately if you've got twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early warning signs of dangerous unwanted effects. Promethazine could cause unwanted side effects that will impair your notions or reactions. Be careful in the event you drive or do anything that needs you to definitely be awake and alert. Avoid alcohol consumption, which could increase some from the negative effects of promethazine. There are many other medicines that can interact with promethazine. Tell your medical professional about all the prescription and over-the-counter medications you utilize. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not start using a new medication without telling your medical professional. Keep a list along with you of each of the medicines you utilize and show this list to the doctor and other healthcare provider who treats you.

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Important safety information:

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Promethazine should not be directed at a kid younger than a couple of years old. Promethazine could cause severe breathing problems or death in a kid younger than 2. Carefully follow your doctor's instructions when giving this medicine to a youngster of any age. Do not use this medication if you might have severe asthma, emphysema, and other breathing problem, or in case you are allergic to promethazine or other phenothiazines like chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you might have certain conditions, you will need a dose adjustment or special tests to soundly use medicines. Before you take promethazine, tell your doctor if you have:

a good seizures;

heart disease or high blood pressure;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or other breathing problem;

sleep apnea (breathing stops during sleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or difficulties with urination;

low levels of calcium with your blood (hypocalcemia); or

if you've ever had a serious unwanted effect while using the promethazine or other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine is harmful for an unborn baby. Tell a medical expert in case you are pregnant or plan to get pregnant during treatment. It just isn't known whether promethazine passes into breast milk or if it might harm a nursing baby. Do not use this medication without telling your doctor in the event you are breast-feeding a baby. Older adults could be more likely to have negative effects from promethazine.

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