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Precautions

Do NOT use Plendil if:

• you happen to be allergic to your ingredient in Plendil
• you possess a good reputation for low blood pressure levels.

Contact your doctor or health care provider without delay if some of these apply to you.

Some medical conditions may interact with Plendil. Tell your doctor or pharmacist if you have any health conditions, particularly if any of the following connect with you:

• if you are pregnant, about to become pregnant, or are breast-feeding
• if you happen to be taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines, foods, or other substances
• when you have heart disease, breathing problems, or a slow heartbeat.

Some medicines may communicate with Plendil. Tell your health care provider if you happen to be taking any other medicines, especially any from the following:

• Barbiturates (eg, phenobarbital), carbamazepine, or hydantoins (eg, phenytoin) for the reason that effectiveness of Plendil may be decreased
• Azole antifungals (eg, ketoconazole), cimetidine, or erythromycin since the actions and unwanted effects of Plendil may be increased
• Macrolide immunosuppressives (eg, tacrolimus) because the actions and unwanted effects of such medicines may be increased.

This may not be a total listing of all interactions which could occur. Ask your medical provider if Plendil may interact to medicines that you take. Check with your health care provider before you begin, stop, or alter the dose from a medicine.

Important safety information:

• Plendil could cause dizziness or lightheadedness. Do not drive, operate machinery, or a single thing else that could be dangerous until you understand how you answer Plendil. Using Plendil alone, with medicines, or with alcohol may lessen your ability to drive or to perform other very dangerous tasks.
• Plendil could potentially cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit or fully stand up slowly, especially within the morning. Also, sit or lay down with the first symbol of dizziness, lightheadedness, or weakness.
• Patients receiving treatment for high blood pressure often feel tired or run down for a few weeks after beginning treatment. Continue taking your medication even when you may not feel quite "normal." Contact your physician or pharmacist about any new symptoms.
• While you happen to be using Plendil, brush and floss your teeth carefully. Also, have regular dental checkups.
• Use Plendil with careful attention in youngsters; safety and effectiveness are not confirmed.
• Pregnancy and breast-feeding: If you plan on becoming pregnant, discuss together with your doctor the benefits and perils of using Plendil when pregnant. It is unknown if this type of drug is excreted in breast milk. Do not breastfeed while taking Plendil.